Proteinase K Solution
Proteinase K Solution
Proteinase K

Proteinase K

Azura PureView™ 50 bp DNA Ladder

Azura PureView™ 50 bp DNA Ladder

Proteinase K Solution

Proteinase K Solution is provided as a 20 mg/mL solution and is of molecular biology grade. It is a broad-spectrum serine protease with very high specific activity. Proteinase K is a recombinant enzyme expressed in Pichia pastoris, and undergoes extensive purification to yield the highest quality product.

Grouped product items
Product NameCatalog No. Qty
Proteinase K Solution 5 mL (1 x 5 mL)
Proteinase K Solution 25 mL (5 x 5 mL)
Proteinase K Solution 100 mL (20 x 5 mL)

It is active under a wide range of reaction conditions, including elevated temperatures and in the presence of SDS. As a result, Proteinase K is widely used for the digestion of proteins, including DNases and RNases, during nucleic acid preparations without compromising the integrity of isolated DNA or RNA. Proteinase K is free of exonucleases, endonucleases, and ribonucleases.


  • • Extraction of DNA and RNA from different starting materials
  • • Purification of target material from contaminating proteins
  • • Removal of DNases and RNases during nucleic acids isolation


  • Recombinant broad-spectrum non-specific protease derived from Tritirachium album and over-expressed in Pichia pastoris
  • Easy to use, 20 mg/mL solution form
  • Molecular Biology Grade
  • High activity and exceptional purity
  • Active at high temperatures (up to 56 °C) and denaturing conditions (e.g. in the presence of urea and/or SDS), which makes it ideal for digesting proteins in variety of applications
  • Stable over a wide pH range: 4.0–12.5 (optimum pH 7.5–8.0)
  • Low residual DNA content (≤ 10 pg/mg)

Proteinase K is shipped on blue ice and should be stored at -20°C .

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